Craig Mill, e-Learning Advisor at the JISC Regional Support Centre NE in Edinburgh, has written a very good guide to creating accessible Word and PDF documents which you can download from the RSC NE e-Inclusion web site. The Guide is licensed under a Creative Commons Attribution which means you can repurpose the content to suit your needs.
Craig has also written a tutorial on how to make Daisy digital talking books using the free Save as Daisy plug-in for Microsoft Word 2003 and 2007 and Open Writer. You can read the tutorial at http://www.rsc-ne-scotland.org.uk/e-inclusion/?p=1262.